CA3132414A1 - Immunomodulating mesenchymal stem cells - Google Patents
Immunomodulating mesenchymal stem cells Download PDFInfo
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- CA3132414A1 CA3132414A1 CA3132414A CA3132414A CA3132414A1 CA 3132414 A1 CA3132414 A1 CA 3132414A1 CA 3132414 A CA3132414 A CA 3132414A CA 3132414 A CA3132414 A CA 3132414A CA 3132414 A1 CA3132414 A1 CA 3132414A1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0668—Mesenchymal stem cells from other natural sources
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/02—Compounds of the arachidonic acid pathway, e.g. prostaglandins, leukotrienes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/03—Compounds acting on the NO pathway, e.g. nitrososarginine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/231—Interleukin-10 (IL-10)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19162270 | 2019-03-12 | ||
| EP19162270.3 | 2019-03-12 | ||
| PCT/EP2020/056625 WO2020182935A1 (en) | 2019-03-12 | 2020-03-12 | Immunomodulating mesenchymal stem cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3132414A1 true CA3132414A1 (en) | 2020-09-17 |
Family
ID=65801891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3132414A Pending CA3132414A1 (en) | 2019-03-12 | 2020-03-12 | Immunomodulating mesenchymal stem cells |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20220154147A1 (en]) |
| EP (1) | EP3938494A1 (en]) |
| JP (1) | JP7572367B2 (en]) |
| KR (1) | KR20210139259A (en]) |
| CN (1) | CN113677789B (en]) |
| AU (1) | AU2020235912A1 (en]) |
| BR (1) | BR112021017738A8 (en]) |
| CA (1) | CA3132414A1 (en]) |
| MX (1) | MX2021010739A (en]) |
| WO (1) | WO2020182935A1 (en]) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023280832A1 (en) * | 2021-07-08 | 2023-01-12 | Boehringer Ingelheim Veterinary Medicine Belgium | Mesenchymal stem cells for use in the treatment of osteoarthritis in animals |
| WO2023280834A1 (en) * | 2021-07-08 | 2023-01-12 | Boehringer Ingelheim Veterinary Medicine Belgium | Mesenchymal stem cells for use in the treatment of atopic dermatitis |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023280836A1 (en) | 2021-07-08 | 2023-01-12 | Boehringer Ingelheim Veterinary Medicine Belgium | Mesenchymal stem cells for use in the treatment of chronic kidney disease |
| WO2023280835A1 (en) | 2021-07-08 | 2023-01-12 | Boehringer Ingelheim Veterinary Medicine Belgium | Mesenchymal stem cells for use in the treatment of chronic gingivostomatitis |
| EP4568687A1 (en) | 2022-08-11 | 2025-06-18 | Boehringer Ingelheim Vetmedica GmbH | Mesenchymal stem cells for use in the treatment of insect-bite hypersensitivity in equines |
| WO2024133886A1 (en) * | 2022-12-23 | 2024-06-27 | Boehringer Ingelheim Veterinary Medicine Belgium | Primed mesenchymal stem cells for use in the treatment of chronic kidney disease |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE316795T1 (de) | 1998-03-18 | 2006-02-15 | Osiris Therapeutics Inc | Mesenchymale stammzellen für die prävention und behandlung von immunantworten bei transplantationen |
| US20080095749A1 (en) * | 2004-03-22 | 2008-04-24 | Sudeepta Aggarwal | Mesenchymal stem cells and uses therefor |
| WO2005093044A1 (en) * | 2004-03-22 | 2005-10-06 | Osiris Therapeutics, Inc. | Mesenchymal stem cells and uses therefor |
| US20140017787A1 (en) | 2010-10-11 | 2014-01-16 | Aline M. Betancourt | Mesenchymal stem cells and related therapies |
| ITRM20110403A1 (it) * | 2011-07-28 | 2013-01-29 | Ospedale Pediatrico Bambino Gesu | Microvescicole isolate da cellule mesenchimali come agenti immunosoppressori. |
| AU2012345630A1 (en) * | 2011-11-30 | 2014-07-17 | Astellas Institute For Regenerative Medicine | Mesenchymal stromal cells and uses related thereto |
| AU2017235446A1 (en) | 2016-03-16 | 2018-11-08 | Cell Medicine, Inc. | Mesenchymal stem cells with enhanced efficacy |
| CA3127868A1 (en) * | 2019-01-31 | 2020-08-06 | Primegen Biotech, Llc | Treatment of atopic dermatitis using mesenchymal stem cells and immune modulation |
-
2020
- 2020-03-12 EP EP20708513.5A patent/EP3938494A1/en active Pending
- 2020-03-12 AU AU2020235912A patent/AU2020235912A1/en active Pending
- 2020-03-12 MX MX2021010739A patent/MX2021010739A/es unknown
- 2020-03-12 CN CN202080018981.6A patent/CN113677789B/zh active Active
- 2020-03-12 WO PCT/EP2020/056625 patent/WO2020182935A1/en active IP Right Grant
- 2020-03-12 BR BR112021017738A patent/BR112021017738A8/pt unknown
- 2020-03-12 CA CA3132414A patent/CA3132414A1/en active Pending
- 2020-03-12 KR KR1020217029168A patent/KR20210139259A/ko active Pending
- 2020-03-12 US US17/436,640 patent/US20220154147A1/en not_active Abandoned
- 2020-03-12 JP JP2021553068A patent/JP7572367B2/ja active Active
-
2024
- 2024-12-23 US US18/999,942 patent/US20250122477A1/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023280832A1 (en) * | 2021-07-08 | 2023-01-12 | Boehringer Ingelheim Veterinary Medicine Belgium | Mesenchymal stem cells for use in the treatment of osteoarthritis in animals |
| WO2023280834A1 (en) * | 2021-07-08 | 2023-01-12 | Boehringer Ingelheim Veterinary Medicine Belgium | Mesenchymal stem cells for use in the treatment of atopic dermatitis |
Also Published As
| Publication number | Publication date |
|---|---|
| JP7572367B2 (ja) | 2024-10-23 |
| BR112021017738A2 (en]) | 2021-11-16 |
| US20220154147A1 (en) | 2022-05-19 |
| EP3938494A1 (en) | 2022-01-19 |
| CN113677789B (zh) | 2024-11-01 |
| BR112021017738A8 (pt) | 2022-08-02 |
| US20250122477A1 (en) | 2025-04-17 |
| KR20210139259A (ko) | 2021-11-22 |
| CN113677789A (zh) | 2021-11-19 |
| WO2020182935A1 (en) | 2020-09-17 |
| AU2020235912A1 (en) | 2021-10-07 |
| MX2021010739A (es) | 2021-12-15 |
| JP2022524764A (ja) | 2022-05-10 |
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